• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    FIXED ANGLE CENTRIFUGAL ROTOR AND THEIR FORMATION METHOD. A fixed angle centrifugal rotor (10,150) is provided. The rotor (10) includes a rotor body (12) having a circumferential side wall (19) and a plurality of tubular cavities (26). Each of the cavities (26) has an open end (21) and a closed end (22) and is configured to receive a sample container therein. A pressure plate (54,154) is operatively coupled to the plurality of tubular cavities (26), so that the pressure plate (54), in combination with the plurality of tubular cavities (26), defines a hollow closed chamber (48) between each adjacent pair of the plurality of tubular cavities (26). Each of the plurality of tubular cavities (26) has a side wall (34b) facing inwardly (28) of the rotor body (12) and a bottom wall (34c) at the closed end (22).
    公开号:BR112012010608B1
    申请号:R112012010608-2
    申请日:2010-11-10
    公开日:2020-10-13
    发明作者:Sina Piramoon
    申请人:Fiberlite Centrifuge, Llc；
    IPC主号:
    专利说明:

    DESCRIPTIVE REPORT REFERENCE REFERENCE
    [0001] This Order claims the priority filing date of US Patent Application Serial No. 12/61 6,276, filed on November 11, 2009, the disclosure of which is hereby incorporated by reference in its entirety. TECHNICAL FIELD
    [0002] This invention generally relates to centrifuge rotors and, more particularly, to a fixed angle rotor for use with a centrifuge. BACKGROUND
    [0003] Centrifuge rotors are typically used in laboratory centrifuges to contain samples during centrifugation. Although centrifuge rotors can vary significantly in construction and size, a common rotor structure is the fixed angle rotor having a solid rotor body with a plurality of cell bore cavities radially distributed within the rotor body and arranged symmetrically around an axis of rotation. Samples are placed in the wells, allowing a plurality of samples to be subjected to centrifugation.
    [0004] Conventional fixed-angle centrifuge rotors can be made of metal or various other materials. However, a known improvement is to build a centrifuge rotor by a process of compression molding and filament winding, in which the rotor is made of an appropriate material, such as composite carbon fiber. For example, a fixed-angle centrifuge rotor can be molded by compression from layers of laminated carbon fiber material coated with resin. Examples of composite centrifuge rotors are described in US Patents 4,738,656, 4,781,669, 4,790,808, 5,505,684, 5,601,522, 5,643,168, 5,759,592, 5,776,400, 5,833,908, 5,876,322 , 6,056,910 and 6,296,798, and in US Patent Application Serial No. 12 / 391,838 (owned by the assignee of the present exhibit) and whose respective exhibits are expressly incorporated herein for reference in their entirety.
    [0005] Since centrifuge rotors are commonly used in high-speed applications, where the speed of centrifuges can exceed hundreds or even thousands of revolutions per minute, centrifuge rotors must withstand the stresses and strains suffered during high speed speed of the loaded rotor. During centrifugation, a rotor with samples loaded into the wells undergoes high forces along radially outward directions from the wells and in directions along the longitudinal axes of the wells, consistent with the centrifugal forces exerted on the sample containers. These forces cause significant tension and stress on the rotor body.
    [0006] A centrifuge rotor must be able to withstand the forces associated with rapid centrifugation over the life of the rotor. A well-known proposal to produce centrifuge rotors that resist such related forces and stresses includes producing the rotor body in a solid structure, with the cavities defined by the properly sized holes or depressions in the rotor, which are configured to receive samples within them. . Rotors of this type, however, are relatively difficult and expensive to manufacture, and their rotation speeds can be limited due to the relatively high mass of the rotors. Therefore, there is a need for centrifuge rotors that provide improved performance in view of the dynamic loads suffered during centrifugation, and that eliminate these and other problems associated with conventional rotors. SUMMARY
    [0007] The present invention overcomes the previous drawbacks and other drawbacks of centrifuge rotors hitherto known for use for centrifugation. Notwithstanding the invention being discussed in connection with certain modalities, it will be understood that the invention is not limited to those modalities. On the contrary, the invention includes all alternatives, modifications and equivalents that can be included within the spirit and scope of the invention.
    [0008] In one embodiment, a fixed-angle centrifuge rotor is provided. The rotor includes a rotor body having a circumferential side wall hull and a plurality of tubular cell bore cavities. Each well has an open and a closed end and is configured to receive a sample container in it. A pressure plate is operatively coupled to the plurality of tubular cavities so that the pressure plate, in combination with the plurality of tubular cavities, defines a hollow chamber enclosed between each adjacent pair of the plurality of tubular cavities. Each of the plurality of tubular cavities has a side wall facing inwardly of the rotor body and a lower wall at the closed end.
    [0009] In one embodiment, the pressure plate has a generally tapered vertical wall part and a lower wall part that extends outward from the generally tapered vertical wall part. The generally tapered vertical wall part of the pressure plate can be operatively coupled to each of the side walls of the plurality of tubular cavities and the lower wall part of the pressure plate can be operatively coupled to a substantial part of each of the lower walls the plurality of tubular cavities. The lower wall part of the pressure plate may include a plurality of circumferentially spaced depressions each configured to operatively couple with a respective wall of the lower walls of the plurality of tubular cavities.
    [0010] The rotor may include an elongated reinforcement that extends around the circumferential side wall of the rotor body. The elongated reinforcement can additionally extend at least partially around an external surface of the pressure plate. In one embodiment, the elongated reinforcement includes a single carbon fiber tow. Alternatively, the reinforcement may comprise multiple fiber tow or unidirectional tape, in other embodiments. Additionally or alternatively, at least one of the rotor body or the pressure plate can be made of carbon fiber. The rotor body and the pressure plate can be a unitary structure molded by compression.
    [0011] In yet another embodiment, a method is provided for forming a centrifuge rotor. The centrifuge rotor has a rotor body including a circumferential side wall and a plurality of tubular cavities, with each cavity having an open end and a closed end. Each well is configured to receive a sample container. The method includes operatively coupling a pressure plate to the closed end of each of the tubular cavities to thereby define a hollow chamber enclosed between each adjacent pair of tubular cavities. Additionally or alternatively, the method may include compression molding the rotor body and the pressure plate into a unitary structure.
    [0012] The method may include the step of applying a reinforcement around an outside of the rotor body and at least partially around an external surface of the pressure plate. Reinforcement application may include continuously rolling a high strength fiber, such as a single carbon fiber tow around the outside of the rotor body. Alternatively, the reinforcement may comprise multiple fiber tow or unidirectional tape. In other modalities. The carbon fiber tow, for example, can be coated with resin, and the method can then include curing the carbon fiber tow to make it integral with the rotor body. The method may additionally or alternatively include helically winding the single carbon fiber around the outside of the rotor body. The method may, additionally or alternatively, include helically winding two or more high strength fibers, such as carbon fiber tow around the outside of the rotor body.
    [0013] The method can also include the steps of obtaining an upper plate having a plurality of holes, inserting the plurality of tubular cavities through the holes, and compression molding the upper plate and the tubular cavities to define a unitary structure. The method may include surrounding a substantial part of each side wall of the tubular cavities with the hollow chambers. In addition or alternatively, the method may include engaging a substantial part of each of the lower walls of the cavities with the pressure plate.
    [0014] The above and other objectives and advantages of the present invention must be made apparent from the accompanying drawings and their description. BRIEF DESCRIPTION OF THE DRAWINGS
    [0015] The attached drawings, which are incorporated and constitute a part of this description, illustrate modalities of the invention and, together with the general description of the invention given above and the detailed description given below, serve to explain the invention.
    [0016] Figure 1 is a perspective view of a centrifuge rotor according to an embodiment of the present invention.
    [0017] Figure 2 is a cross-sectional view taken generally along line 2-2 of Figure 1.
    [0018] Figure 2A is a partially interrupted view of a rotor base in Figures 1-2.
    [0019] Figure 3 is a view of the centrifuge rotor of Figures 1-2, partially disassembled.
    [0020] Figure 3A is a schematic representation of an example method for forming a first rotor part of Figures 1-3.
    [0021] Figure 4A is a schematic diagram of a rotor body of the centrifuge rotor of Figures 1-3.
    [0022] Figure 4B is an elevation view of the rotor body of Figure 4A with a reinforcement rolled over it, according to an embodiment of the present invention.
    [0023] Figure 4C is an elevation view of the rotor body of Figure 4A with multiple reinforcements rolled over it, according to an embodiment of the present invention.
    [0024] Figure 4D is an elevation view of the rotor body of Figure 4A with multiple reinforcements rolled over it according to another embodiment of the present invention.
    [0025] Figures 5A-5E are plan views of a rotor body with reinforcements rolled over it, according to an embodiment of the present invention.
    [0026] Figure 6 is a perspective view of a centrifuge rotor, partially disassembled, according to another embodiment of the invention.
    [0027] Figure 7 is a cross-sectional view of part of the centrifuge rotor in Figure 6. DETAILED DESCRIPTION
    [0028] Figures 1-3 illustrate a centrifuge rotor 10, for example, according to an embodiment of the present invention. The rotor 10 includes a rotor body 12 having an upper surface 14 and being symmetrical about an axis of rotation 16 of the rotor body 12, around which the samples (not shown) are centrifuged. An elongated reinforcement 18 extends continuously around an external surface 20, generally smooth, of a side wall 19, which extends circumferentially (figure 3), of the rotor body 12. When used here, the term "generally smooth" it is used to describe the outer surface 20 which is intended to be used to describe the surface 20 which does not have a staggered configuration, and is generally free of sharp corners or edges. In this regard, the term defined above is not intended to define the surface roughness of the surface 20. In addition, the rotor body 12 can be formed so that the generally free external surface 20 does not require machining or additional finishing before application of the reinforcement 18.
    [0029] The rotor 10 includes a plurality (e.g. 4 or 6) of tubular cell bore cavities 26 extending from the upper surface 14 and towards an interior 28 (figures 2A and 3) of the rotor body 12 When used here, the term “interior”, when used with reference to the interior 28 of the rotor 10, refers to that part of the rotor 10 that is enclosed by the outer walls defining the overall shape of the rotor 10. Each tubular cavity has a open end 21 on the upper surface 14 and an opposite closed end 22. Each of the wells 26 is appropriately sized and shaped to receive in it one of the sample containers (not shown) for centrifugal rotation of the same about the axis 16. Each of the cavities 26 is defined by a side wall 34 having an appropriately chosen thickness and cross section profile. Each side wall 34 has a first face 34a defining a container reception, first face of cavities 26, and a second opposite face 34b facing inward 28 of the rotor body 12. When used here, the term "tubular" refers to cavities having any cross-sectional shape, including, for example and without limitation, rounded shapes (for example, oval, circular or conical), quadrilateral shapes, regular polygonal or irregular polygonal shapes or any other suitable shape. Therefore, this term is not intended to be limited to the profile of the generally circular cross section of the exemplary tubular cavities 26, illustrated in the Figures.
    [0030] With continued reference to Figures 1-3 and still with reference to Figure 3A, the production of the rotor 10 of this embodiment can include forming the tubular cavities 26 together with portions of the rotor body 12 defining the upper surface 14. More specifically, and with particular reference to Figure 3A, an upper plate 40 can be obtained, having a plurality of holes 42 corresponding to each of the cavities 26. Each of the tubular cavities 26 is then inserted (in the direction of the arrow 43) through one of the holes 42 and pressure and heat are then applied to the tubular cavities 26 and the upper plate 40 to thus form a unitary structure. The tubular cavities 26 and the upper plate 40 are made of appropriately chosen materials. For example and without limitation, the tubular cavities 26 and the upper plate 40 can be made of a light but strong material, such as carbon fiber, which facilitates the minimization of the total mass of the rotor 10. In the illustrated embodiment, moreover, the tubular cavities 26 are formed so that respective portions of each of the second faces 34b are surrounded by a pair of adjacent hollow chambers 48 (figures 2A and 3) within the interior 28 of the rotor body 12, which further facilitates minimization of the total mass of the rotor 10. It is contemplated, however, that alternative modalities may be such that the tubular cavities 26 are partially, additionally surrounded, inside 28, by a light material that does not add significant mass to the rotor 10.
    [0031] Hollow chambers 48 are further defined by the coupling of a pressure plate 54 of the rotor 10 to the rotor body 12, as explained in more detail below. More specifically, when the pressure plate 54 and the rotor body 12 are coupled together, a generally tapered vertical wall part 54a, centrally positioned, of the pressure plate 54, engages (for example, leans against) a part radially inward facing each of the second faces 34b of the tubular cavities 26, thus defining the plurality of closed hollow chambers 48, as best illustrated in Figures 2A and 3. In this regard, the hollow chambers 48, together with the generally tapered vertical wall part 54a and the upwardly facing portions of a lower wall part 54b of the pressure plate 54 further define the interior 28 of the rotor 10.
    [0032] Furthermore, in the illustrated embodiment, all of the tubular cavities 26 are formed so that the second faces 34b of each pair of adjacent tubular cavities 26 are facing a common closed hollow chamber 48. It is taken into account that, alternatively to embodiments illustrated in the Figures, a rotor may have cavities 26, each exposed to more than two hollow chambers 48. Each of the hollow chambers closed 48 in the embodiment of Figures 2-2A is further defined by the circumferential side wall 19 of the rotor body 12 In this regard, therefore, the operative coupling between the pressure plate 54 and the side walls 34 of the cavities 26 defines a plurality of hollow closed chambers 48 delimited by the side wall 19, respective lateral portions of the second faces 34b of two tubular cavities adjacent 26 and the central wall part 54a of the pressure plate 54. It is taken into account, however, that such a definition of the hollow chambers 48 is merely exemplified captive and thus is not intended to be limiting. Also, in the illustrated embodiment, a substantial part of each of the second faces 34b is surrounded by the hollow space (i.e., corresponding to a pair of adjacent chambers of the closed hollow chambers 48). As used herein, the term "substantial", when used to describe the part of a second face 34b of a tubular cavity 26 that is surrounded by a hollow chamber 48, is intended to describe a modality in which at least about 40% and preferably between about 40% and about 60% of a particular second face 34b is surrounded by the hollow space.
    [0033] With particular reference to Figures 2 and 3, the rotor 10 includes, as discussed above, a pressure plate 54 which defines the base of the rotor 10 and which is operatively coupled to the tubular cavities 26. Notably, the pressure plate 54 it is operatively coupled to the closed ends 22 of the cavities 26 to support the tubular cavities 26 during the high speed rotation of the rotor 10, thus providing structural integrity and minimizing the probability of failure of the rotor 10. In use, when the rotor 10 is rotated, the pressure plate 54 applies torque to the tubular cavities 26 and the rotor body 12. More specifically, the lower wall part 54b of the pressure plate 54 includes a plurality of depressions or circumferentially spaced cavities 56, each configured to receive and engage, in relation to the abutment, a respective wall of the lower walls 34c at the closed ends 22 of the tubular cavities 26 during the high speed rotation of the break 10. For this purpose, the coupling between the pressure plate 54 and the rotor body 12 can be such that the pressure plate 54 exerts pressure against each of the lower walls 34c, thus providing the required support. The depressions 56 are suitably shaped so as to contact a substantial part of one of the lower walls 34c. This facilitates the minimization of the possibility of stress concentration associated with high-speed rotation on the pressure plate 54. In this particular embodiment, for example, each of the depressions 56 has a generally flat surface corresponding to the also generally flat shape of the lower walls 34c of the cavities 26. In addition, in the illustrated embodiment, when the pressure plate 54 is engaged with the rotor body 12, the abutment engagement of the conically shaped central part 54a of the pressure plate 54 with the tubular cavities 26 further provides support for the tubular cavities 26 during the high speed rotation of the rotor 10.
    [0034] The coupling between pressure plate 54 and rotor body 12, in this embodiment, is facilitated by a fastener, such as a retaining nut 60, for example, and also by means of compression molding of pressure plate 54 and tubular cavities 26 to each other, thus producing a unitary structure. More specifically and with particular reference to Figures 2 and 2A, the retaining nut 60 threadedly engages an externally threaded part 61 of a rotor hub 62 which, as discussed below, facilitates the engagement of rotor 10 by a centrifugal spindle (not shown) to allow high-speed rotation of the rotor 10.0 engagement of the nut 60 is carried out from the underside of the pressure plate 54, with such an engagement thus securing the rotor hub 62 and the central part 54a of the pressure plate 54 um in relation to the other, as illustrated in the Figures. The rotor hub 62, in turn, is threadedly attached to a rotor insert 64 that is positioned inside 28 of the rotor body 12 and engaged with a central inner portion 12d of the rotor body 12.
    [0035] Those of ordinary skill in the art will immediately take into account that the illustrated coupling between the pressure plate 54 and rotor body 12 is exemplary, rather than intended to be limiting, insofar as variations in the type of coupling among these components are also contemplated. Such coupling can be further facilitated by reinforcement 18, which can, for example, be applied by winding (for example, helical winding) a continuous high-strength fiber yarn, such as a single tow, or a continuous yarn of fiber carbon (for example, a resin coated carbon fiber) around the outer surface 20 of the rotor body 12 and over exposed portions of the pressure plate 54. Especially when the fiber is resin coated, after compression molding (ie , in which heat and pressure are applied), the pressure plate 54 and the rotor body 12 become a unitary structure. In a specific embodiment, the production of rotor 10 may include curing a carbon fiber coated with tow resin or continuous reinforcement wire 18 so that the continuous wire becomes integral with the rotor body 12 and / or the pressure plate 54. In one aspect, the pressure plate 54 is made of an appropriately chosen material. For example and without limitation, the pressure plate 54 can be made of carbon fiber, to further minimize the total mass of the rotor 10.
    [0036] Referring again to Figures 2 and 3, in use, rotor 10 is mounted on rotor hub 62, which is in turn coupled to the centrifuge spindle (not shown) via two or more pins received inside respective projections 63 at the base of cube 62 and other structures to be described in more detail below. The rotor 10 includes, as discussed above, a rotor insert 64 which is threadedly engaged in the rotor hub 62. Insert 64 includes a plurality of sections 64a which are received within cooperating depressions in the central inner part 12d of the rotor body 12 Once the rotor 10 is seated on the rotor hub 62, a hub retainer 66 is attached to the top of the hub 62 to further facilitate the retention of the rotor body 12, the pressure plate 54, the hub 62 and insertion 64 in place relative to each other. A cover 70 of the rotor 10 is coupled to the rotor body 12 via a cover screw 74 which is received through a central threaded opening 62a of hub 62. In addition, in this embodiment, a sealing element, such as a ring in The 75 (figure 2), for example, still facilitates the coupling between the cap 70 and the rotor body 12. The cap 70 blocks access to the sample containers kept in the cavities 26 during high speed rotation. Once the cap 70 is secured in place by engaging the cap screw 74 with the central opening 62a, the cap screw 78 is inserted through a hole 74a of the cap screw 74. The rotation of the cap screw 78, in turn, it allows the threaded engagement of the fixing screw 78 with a cooperating threaded part of the centrifuge spindle (not shown) which, therefore, attach rotor 10 to the centrifuge spindle. The centrifuge spindle can then be actuated to drive rotor 10 at high speed centrifugal rotation. As those of ordinary skill in the art will take into account, one or more of the rotor assembly components described above can be made of any suitable metallic or non-metallic material.
    [0037] With reference to Figures 4A-4D, details of an example apparatus and an example method for applying reinforcement 18 are provided. A guide 80 is used to apply a continuous wire 18a to the outer surface 20 of the body. rotor 12 along a generally helical reinforcement path 82. The path of the guide 80 with respect to the rotor body 12 defines the path 82 of the continuous wire 18a. The guide 80 can have multiple degrees of freedom to ensure that the guide 80 correctly guides the continuous wire 18a over the generally helical path 82, while being substantially normal to the surface of the rotor body 12. In one embodiment, the reinforcement guide 80 can have five degrees of freedom, more specifically, the vertical and horizontal position of the guide 80, the pitch and yaw of the guide 80 and the radial position of the guide 80 with respect to the axis of rotation 16. The continuous wire 18a can be wound over the rotor body 12 by rotating the body 12 around the axis 16 during manipulation of the guide 80 to apply the continuous wire 18a along the desired path 82. The rotor body 12 can be held in a generally fixed position while being rotated about axis 16, or the rotor body 12 can be moved relative to the guide 80 to define the desired path 82 for the continuous wire 18a when it is wound over the rotor body 12 Alternatively, ag urea 80 can be held in a generally fixed position, while the rotor body 12 is rotated about the axis 16 and moved relative to the guide 80 to apply the continuous wire 18a along the desired path 82.
    [0038] With particular reference to Figure 4A, a schematic illustration of a side view of the rotor body 12 is shown. The arrow G denotes the outward force exerted by the center of gravity of a charged cavity 26 during centrifugation. The arrows G1 and G2 denote the components of this normal force at the outer surface 20 of the rotor body 12 and along the central longitudinal axis C of the cavity 26, respectively. The diagram in Figure 5A also represents a helical reinforcement path 82, for example. The helical reinforcement path 82 may include one or more of the path components 82a and 82b. Path component 82a intersects a point 100 which is defined by the radial projection of the center of gravity G of a charged cavity 26, intersecting with the outer surface 20 of the rotor body 12. Another path component 82b intersects a point 102 which is defined by intersection of the longitudinal axis C of a cavity 26 with the outer surface 20 at the lower end 12b of the rotor body 12. The guide 80 tightly winds the continuous wire 18a around the smooth outer surface 20 of the rotor body 12. In one embodiment, Sufficient tension is applied to the continuous wire 18a by the guide 80 for the particular fiber path and the rotor shape, so that the normal forces exerted on the continuous wire 18a by the rotor body 12 substantially eliminate the slip of the continuous wire 18a with respect to to the smooth outer surface 20 of the rotor body 12.
    [0039] Points 100 and 102 are shown on the outer surface 20 of the substantially smooth rotor body 12. Point 100 corresponds to the radial projection, on the outer surface 20 of the rotor body 12, of the location of the center of gravity of a loaded cavity. Point 102 corresponds to the intersection of a central longitudinal axis C of one of the cavities 26 with the outer surface of a lower end 12b of the rotor body 12. In one embodiment, the reinforcement path 82 overlaps one or both of these points 100, 102 so that at least two portions of continuous wire 18a interconnect to cover one or both points 100, 102. Each interleaving can be formed, for example, by overlapping portions of continuous wire 18a and applied resin. In this regard, vertical interlacing straps 112 and horizontal interlacing straps 114 (figure 1) can be formed by the layers of material defining reinforcement 18 around the rotor body 12. One or more of the vertical straps 112 can be positioned in the radial projection of one of the C axes on the surface 20 of the rotor body 12. In an example method, one of the horizontal straps 114 can be arranged at the center of gravity of the loaded cavities 26 so that the reinforcement path 82 intercepts selected points, such as like points 100 and 102, for example.
    [0040] With particular reference to Figures 4C and 4D, a variation of the embodiment of Figures 4A-4B is illustrated. In this embodiment, two continuous wires 18a, 18b are simultaneously applied to the external surface 20 of the rotor body 12 by respective guides 80a and 80b, in order to define the reinforcement 18. The starting points of the continuous wires 18a, 18b can be positioned in the opposite sides of the rotor body 12 to be wound in opposition to each other, as shown in Figure 4C, or the starting points can be positioned next to each other, as shown in Figure 4D. Each reinforcement guide 80a, 80b can have as many as five degrees of freedom, as discussed above. The reinforcement path 82 is generally helical and extends around the outer surface 20 of the rotor body 12, while also moving axially between an upper end 12a and the lower end 12b of the body 12. The reinforcement path 82 can also extend they extend at least partially around the base edge at the lower end 12b of the rotor body 12 and at least partially cover the pressure plate 54, for example. Point 102 is also shown in Figure 4C, and points 100 and 102 are shown in Figure 4D. Where multiple reinforcement strands 18a, 18b are used to construct reinforcement 18, an intersection of the strand 18a with the strand 18b can be positioned at the projected center of gravity 100 or longitudinal axis intersection point 102.
    [0041] In the embodiment shown and described here, the continuous wire 18a can still be applied to the rotor body 12 along a path that extends in a generally circumferential direction at least partially around the upper end 12a of the rotor body 12 to thus define a lip 118 (figure 2) near the upper end 12a of the rotor body 12. For this purpose and as shown in Figures 4B to 4D, a fixed accessory 124 can be placed on the upper end 12a of the rotor body 12 so that the continuous wire 18a is wound around the generally cylindrical fixed accessory 124 to form the lip 118 (figure 2) positioned above the upper end 12a of the rotor body 12.
    [0042] Figures 5A to 5E illustrate the winding progression of continuous wire 18a to form layers of reinforcement material. Specifically, the continuous wire 18a is wound repeatedly around the rotor body 12 along the reinforcement path 82 (figure 4A). This repeated winding of the continuous wire 18a around the outer surface 20 of the rotor body 12 produces a plurality of layers of material covering the rotor body 12, which thus define the reinforcement 18. In a specific embodiment, the continuous wire 18a can be, for example, a continuous carbon fiber filament or yarn, as discussed above. The continuous yarn or filament may be a composite material of carbon fiber and resin that, upon completion of the winding process, is cured to form an integral centrifuge rotor 10. Alternatively, several other high-traction, high-modulus materials , such as fiberglass, synthetic fiber such as para-aramid fiber (eg Kevlar®), thermoplastic filament, such as ultra high molecular weight polyethylene, metal wire, or other materials suitable for reinforcing the rotor body 12, can be used in place of carbon fiber. Any of such materials can be used as a single continuous filament or as multiple filaments and many of such materials can be applied with a resin coating that can be hardened in a manner analogous to the hardening of resin coated carbon fiber. As will be taken into account by the description above, the reinforcement may comprise a single fiber tow, multiple fiber tow or unidirectional tape in various alternative embodiments.
    [0043] Referring now to Figures 6 and 7, an alternative embodiment of a rotor 150 includes a pressure plate 154 which is slightly modified in relation to the pressure plate 54 of the preceding Figures. To facilitate understanding, the same reference numbers in Figures 6 and 7 refer to similar characteristics in the previous Figures. Pressure plate 154 has a plurality of depressions or circumferentially spaced cavities 156 similar in function and structure to the depressions or cavities 56 of the preceding Figures. Each of the cavities 156 has a lip or lip 160 which is configured to tightly and frictionally engage a shoulder 161 at the closed end 22 of one of the tubular cavities 26 (figure 2). The tight engagement between the lips 160 and the corresponding shoulders 161 of the tubular cavities 26 facilitates the transfer of torque from the pressure plate 154 to the tubular cavities 26 during the centrifugal rotation of the rotor 150. For this purpose, each of the lips 160 it extends substantially around the periphery of the corresponding closed end 22 of a tubular cavity 26 and still extends close to the peripheral edge of the pressure plate 154. In addition, each lip 160 extends upwards (in the direction of the axis 16) to from the base surface of the corresponding cavity depression 156.
    [0044] In another aspect of the alternative rotor 150, the pressure plate 154 is also designed to minimize its total weight, and thus the total mass of the rotor 150. More specifically, the pressure plate 154 includes a plurality of weight-minimizing depressions, circumferentially spaced, of cut-out portions 164 positioned adjacent to some of the depressions or cavities 156. These cut-out portions 164 are reduced in thickness in order to reduce the mass of the pressure plate compared to, for example, the pressure plate 54 of the preceding Figures, which do not include cut-out portions. Although the example pressure plate 154 has four tubular cavities 26 and four cut-out portions 164, it is envisaged that it may have, instead, any other number of tubular cavities 26 and / or cut-out portions 164.
    [0045] Although several aspects according to the principles of the invention have been illustrated by the description of various modalities and although the modalities have been described in considerable detail, they are not intended to restrict or limit in any way the scope of the invention to such detail. The various features shown and described here can be used alone or in any combination. Additional advantages and modifications will clearly appear to those skilled in the art. The invention in its broadest aspects, therefore, is not limited to specific details, representative apparatus and methods and illustrative examples shown and described. Therefore, exits can be made from these details without departing from the scope of the general inventive concept.
    权利要求:
    Claims (16)
    [0001]
    1 - Fixed Angle Centrifugal Rotor, (10, 150), comprising: a rotor body (12) having a circumferential side wall (19) and a plurality of tubular cavities (26), each cavity (26) having an end open (21) and a closed end (22) and being configured to receive a sample container, characterized by: a pressure plate (54, 154) operatively coupled to the plurality of tubular cavities (26) so that the pressure plate pressure (54, 154), in combination with the plurality of tubular cavities (26), defines a closed hollow chamber (48) between each adjacent pair of the plurality of tubular cavities (26); and the pressure plate (54, 154) has a plurality of circumferentially spaced depressions (56, 156), each pair being configured to operatively couple with a respective of the plurality of tubular cavities (26).
    [0002]
    2 - Fixed Angle Centrifugal Rotor (10, 150), according to Claim 1, characterized in that each of the plurality of tubular cavities (26) has a side wall (34b) facing an interior (28) of the rotor body (12) and a bottom wall (34c) at the closed end (22).
    [0003]
    3 - Fixed Angle Centrifugal Rotor (10, 150) according to Claim 2, characterized in that the pressure plate (54, 154) comprises a vertical tapered wall part (54a) and a lower wall part ( 54b) extending outwardly from the vertical tapered wall part (54a), the circumferentially spaced depressions (56, 156) being located in the bottom wall part (546).
    [0004]
    4 - Fixed Angle Centrifugal Rotor (10, 150), according to Claim 3, characterized in that the vertical tapered wall part (54a) of the pressure plate (54, 154) is operatively coupled to each of the walls sides (34b) of the plurality of tubular cavities (26) and the bottom wall part (54b) of the pressure plate (54, 154) is operatively coupled to a part of each of the bottom walls (34c) of the plurality of tubular cavities (26).
    [0005]
    5 - Fixed Angle Centrifugal Rotor, (10, 150), according to Claim 1, characterized in that it further comprises: an elongated reinforcement (18) extending around the circumferential side wall (19) of the rotor body ( 12), wherein the elongated reinforcement (18) extends at least partially around an outer surface of the pressure plate (54, 154).
    [0006]
    6 - Fixed Angle Centrifugal Rotor (10, 150), according to any preceding Claim, characterized in that at least one of the rotor body (12) or the pressure plate (54, 154) is made of carbon fiber .
    [0007]
    Fixed Angle Centrifugal Rotor (10, 150) according to any preceding claim, characterized in that the rotor body (12) and the pressure plate (54, 154) define a unitary structure molded by compression.
    [0008]
    Fixed Angle Centrifugal Rotor (10, 150) according to any preceding claim, characterized in that the pressure plate (154) includes a plurality of circumferentially spaced cut-out parts (164) located between the adjacent pairs of depressions ( 156) and being configured to minimize the weight of the pressure plate (154).
    [0009]
    9 - Fixed Angle Centrifugal Rotor, (10, 150), according to any preceding Claim, characterized in that the pressure plate (154) includes a plurality of lips (160) configured to friction fit the closed ends of the respective cavities tubular (26).
    [0010]
    10 - Method For Forming Centrifugal Rotor, as defined in Claim 1 and its dependents, having a rotor body (12), including a circumferential side wall (19) and a plurality of tubular cavities (26), each cavity (26) an open end (21) and a closed end (22) and being configured to receive a sample container in it, characterized by: operatively coupling a pressure plate (54, 154) having a plurality of circumferentially spaced depressions (56, 156 ) to the closed end (22) of each of the cavities (26) to thereby define a hollow closed chamber (48) between each adjacent pair of tubular cavities (26), each of which is of the plurality of circumferentially spaced depressions ( 56, 156) of the pressure plate (54, 154) is operatively coupled to the respective of the tubular cavities (26).
    [0011]
    11 - Method for Forming Centrifugal Rotor, according to Claim 10, characterized in that it further comprises: compression molding of the pressure plate (54, 154) and the rotor body (12) to define a unitary structure.
    [0012]
    Method for Forming Centrifugal Rotor, according to any one of Claims 10-11, characterized in that it further comprises: applying a reinforcement (18) around an exterior of the rotor body (12) and at least partially around an outer surface of the pressure plate (54, 154).
    [0013]
    13 - Method for Forming Centrifugal Rotor, according to Claim 12, characterized in that the reinforcement (18) is coated with resin, the method further comprising: curing the reinforcement (18) to make it integral with the rotor body ( 12).
    [0014]
    Method for Forming Centrifugal Rotor, according to any of Claims 10-13, characterized in that it further comprises: obtaining a top plate (40) having a plurality of holes (42); insert the plurality of tubular cavities (26) through the holes (42), and compress the upper plate (40) and the tubular cavities (26) by compression to define a unitary structure.
    [0015]
    Method for Forming Centrifugal Rotor, according to any of Claims 10-14, characterized in that each tubular cavity (26) has a side wall (34b) facing an interior of the rotor body (12), comprising still the method: surround a part of the side walls (34b) of each of the cavities (26) with the hollow closed chambers (48).
    [0016]
    Method for forming a centrifugal rotor, according to any one of Claims 10-15, characterized in that each tubular cavity (26) has a bottom wall (34c) at the closed end (22) and operatively coupling the pressure plate (54 154) at the closed end (22) of each of the cavities (26) includes wrapping a part of each of the bottom walls (34c) of the cavities with the circumferentially spaced depressions (56, 156) of the pressure plate (54, 154).
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US3248046A|1965-07-02|1966-04-26|Jr John P Feltman|High speed rotor used for centrifugal separation|
    JPS6020071B2|1980-02-04|1985-05-20|Hitachi Koki Kk|
    GB2098516B|1981-04-14|1985-04-24|Fisons Plc|Centrifuge rotor|
    US4449965A|1982-10-04|1984-05-22|Beckman Instruments, Inc.|Shell type centrifuge rotor having controlled windage|
    US4484906A|1983-05-02|1984-11-27|Beckman Instruments, Inc.|Shell type centrifuge rotor retaining ruptured tube sample|
    JPH045503B2|1983-10-24|1992-01-31|
    JPH045505B2|1983-11-29|1992-01-31|
    JPS61101262A|1984-10-24|1986-05-20|Hitachi Chem Co Ltd|Rotor for centrifugal separator|
    US4860610A|1984-12-21|1989-08-29|E. I. Du Pont De Nemours And Company|Wound rotor element and centrifuge fabricated therefrom|
    US4675001A|1985-07-23|1987-06-23|E. I. Du Pont De Nemours And Company|Centrifuge rotor|
    US4991462A|1985-12-06|1991-02-12|E. I. Du Pont De Nemours And Company|Flexible composite ultracentrifuge rotor|
    US4817453A|1985-12-06|1989-04-04|E. I. Dupont De Nemours And Company|Fiber reinforced centrifuge rotor|
    US4738656A|1986-04-09|1988-04-19|Beckman Instruments, Inc.|Composite material rotor|
    US5057071A|1986-04-09|1991-10-15|Beckman Instruments, Inc.|Hybrid centrifuge rotor|
    US4701157A|1986-08-19|1987-10-20|E. I. Du Pont De Nemours And Company|Laminated arm composite centrifuge rotor|
    US5206988A|1986-09-10|1993-05-04|Beckman Instruments, Inc.|Hybrid ultra-centrifuge rotor with balancing ring and method of manufacture|
    NL8700642A|1987-03-18|1988-10-17|Ultra Centrifuge Nederland Nv|CENTRIFUGE FOR SEPARATING LIQUIDS.|
    JPH0761455B2|1987-05-28|1995-07-05|ベツクマンインスツルメンツインコ−ポレ−テツド|Centrifuge rotor|
    US4790808A|1987-06-05|1988-12-13|Beckman Instruments, Inc.|Composite material centrifuge rotor|
    US4781669A|1987-06-05|1988-11-01|Beckman Instruments, Inc.|Composite material centrifuge rotor|
    JPH01135550A|1987-11-21|1989-05-29|Hitachi Koki Co Ltd|Rotor for centrifuge|
    US4944721A|1988-11-09|1990-07-31|E. I. Du Pont De Nemours And Company|Cavity sealing system for a centrifuge rotor|
    JPH0725230Y2|1988-11-09|1995-06-07|株式会社久保田製作所|Centrifuge rotor|
    US4927406A|1988-12-15|1990-05-22|Beckman Instruments, Inc.|Spring biased drive socket insert for centrifuge rotors|
    US5562584A|1989-08-02|1996-10-08|E. I. Du Pont De Nemours And Company|Tension band centrifuge rotor|
    US5545118A|1989-08-02|1996-08-13|Romanauskas; William A.|Tension band centrifuge rotor|
    DE9016288U1|1990-11-30|1991-10-10|Fa. Andreas Hettich, 7200 Tuttlingen, De|
    JPH07500284A|1991-10-21|1995-01-12|
    WO1993025315A1|1992-06-10|1993-12-23|Mohammad Ghassem Malekmadani|Fixed-angle composite centrifuge rotor|
    AU5994794A|1993-01-14|1994-08-15|Composite Rotors, Inc.|Ultra-light composite centrifuge rotor|
    US5362300A|1993-05-27|1994-11-08|E. I. Du Pont De Nemours And Company|Shell-type centrifuge rotor|
    US5540126A|1994-05-26|1996-07-30|Piramoon Technologies|Automatic lay-up machine for composite fiber tape|
    US5601522A|1994-05-26|1997-02-11|Piramoon Technologies|Fixed angle composite centrifuge rotor fabrication with filament windings on angled surfaces|
    US5505684A|1994-08-10|1996-04-09|Piramoon Technologies, Inc.|Centrifuge construction having central stator|
    US5833908A|1995-05-01|1998-11-10|Piramoon Technologies, Inc.|Method for compression molding a fixed centrifuge rotor having sample tube aperture inserts|
    US5643168A|1995-05-01|1997-07-01|Piramoon Technologies, Inc.|Compression molded composite material fixed angle rotor|
    US6056910A|1995-05-01|2000-05-02|Piramoon Technologies, Inc.|Process for making a net shaped composite material fixed angle centrifuge rotor|
    JPH11504873A|1995-05-01|1999-05-11|ピラムーンテクノロジーズ，インコーポレイティド|Fixed angle rotor made of compression molded synthetic material|
    US5558616A|1995-09-07|1996-09-24|E. I. Du Pont De Nemours And Company|Centrifuge rotor cover having container supports thereon|
    US5683341A|1996-03-14|1997-11-04|Piramoon Technologies, Inc.|Quill shaft suspension for centrifuge rotor having central stator|
    US5876322A|1997-02-03|1999-03-02|Piramoon; Alireza|Helically woven composite rotor|
    US5972264A|1997-06-06|1999-10-26|Composite Rotor, Inc.|Resin transfer molding of a centrifuge rotor|
    US6296798B1|1998-03-16|2001-10-02|Piramoon Technologies, Inc.|Process for compression molding a composite rotor with scalloped bottom|
    US6190300B1|2000-03-10|2001-02-20|Labnet International Inc.|Centrifuge rotor adapted for use with centrifuge tube strips|
    DE102004062232B4|2004-12-23|2013-01-10|Thermo Electron Led Gmbh|Rotor for laboratory centrifuges|
    JP4941881B2|2006-02-23|2012-05-30|日立工機株式会社|Centrifuge rotor and centrifuge|
    JP2008119649A|2006-11-15|2008-05-29|Hitachi Koki Co Ltd|Rotor for centrifuge and centrifuge|
    US8147392B2|2009-02-24|2012-04-03|Fiberlite Centrifuge, Llc|Fixed angle centrifuge rotor with helically wound reinforcement|
    EP2269740B1|2009-06-30|2015-11-04|Hitachi Koki CO., LTD.|Centrifugal separator|
    US8323169B2|2009-11-11|2012-12-04|Fiberlite Centrifuge, Llc|Fixed angle centrifuge rotor with tubular cavities and related methods|US8147393B2|2009-01-19|2012-04-03|Fiberlite Centrifuge, Llc|Composite centrifuge rotor|
    US8147392B2|2009-02-24|2012-04-03|Fiberlite Centrifuge, Llc|Fixed angle centrifuge rotor with helically wound reinforcement|
    US8211002B2|2009-04-24|2012-07-03|Fiberlite Centrifuge, Llc|Reinforced swing bucket for use with a centrifuge rotor|
    US8323170B2|2009-04-24|2012-12-04|Fiberlite Centrifuge, Llc|Swing bucket centrifuge rotor including a reinforcement layer|
    US8323169B2|2009-11-11|2012-12-04|Fiberlite Centrifuge, Llc|Fixed angle centrifuge rotor with tubular cavities and related methods|
    US8328708B2|2009-12-07|2012-12-11|Fiberlite Centrifuge, Llc|Fiber-reinforced swing bucket centrifuge rotor and related methods|
    EP2705903A1|2012-09-06|2014-03-12|Eppendorf AG|Rotor device, centrifuge vessel and centrifuge and method for producing same|
    JP6186161B2|2013-04-10|2017-08-23|あおい精機株式会社|Centrifuge|
    US9649641B2|2014-08-05|2017-05-16|Anthony Walter Demsia|Spring operated swing out rotor system and method for a centrifuge|
    CN104549783A|2014-12-26|2015-04-29|湖南平凡科技有限公司|Horizontal rotor and centrifugal machine with horizontal rotor|
    US10086383B2|2015-01-05|2018-10-02|Fiberlite Centrifuge, Llc|Fixed angle centrifuge rotor having torque transfer members|
    CN107913804A|2016-10-11|2018-04-17|湖南湘仪实验室仪器开发有限公司|A kind of vast capacity centrifuge-head|
    USD877929S1|2018-03-19|2020-03-10|Fiberlite Centrifuge, Llc|Centrifuge rotor|
    CN112469505A|2018-05-11|2021-03-09|拜克门寇尔特公司|Centrifuge rotor and container arrangement|
    CN108437488A|2018-05-28|2018-08-24|长沙高新技术产业开发区湘仪离心机仪器有限公司|A kind of production method of carbon fibre composite centrifuge rotor|
    DE102018120007A1|2018-08-16|2020-02-20|Eppendorf Ag|Fixed-angle rotor|
    CN109692761A|2018-12-25|2019-04-30|山东博森医学工程技术有限公司|A kind of platelet rich plasma extraction element and its method|
    US20200306769A1|2019-03-29|2020-10-01|Fiberlite Centrifuge Llc|Fixed angle centrifuge rotor with tubular cavities and related methods|
    WO2021158749A1|2020-02-04|2021-08-12|Fiberlite Centrifuge Llc|System and method for balancing a centrifuge rotor|
    WO2021252456A1|2020-06-09|2021-12-16|Fiberlite Centrifuge Llc|Batch bioprocessing centrifuge rotor|
    WO2022035952A1|2020-08-14|2022-02-17|Fiberlite Centrifuge Llc|Continuous bioprocessing centrifuge rotor|
    法律状态:
    2020-02-04| B06U| Preliminary requirement: requests with searches performed by other patent offices: suspension of the patent application procedure|
    2020-05-26| B09A| Decision: intention to grant|
    2020-10-13| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/11/2010, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    US12/616,276|2009-11-11|
    US12/616,276|US8323169B2|2009-11-11|2009-11-11|Fixed angle centrifuge rotor with tubular cavities and related methods|
    PCT/US2010/056171|WO2011060030A1|2009-11-11|2010-11-10|Fixed angle centrifuge rotor with tubular cavities and related methods|
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